Change is everywhere with regard to the transformation of teaching and learning, including infrastructure. Open standards that enable plug-and-play digital resources, content discovery and curation, real-time learning analytics, and competency-based strategies are either in the market or nearly there. High speed R&E networks are enabling this new generation learning infrastructure environment, which will go hand-in-hand with evolving strategies and leadership, much like that required when widespread online learning and the use of the LMS first took hold over a decade ago. No one has all the answers at this moment, but it is clear that new collaborations are beginning to significantly shape next-gen learning. Higher education collaborations between US, Europe, Asia, Australia and other parts of the world figure prominently in the potential for massive scaling of standards. We'll outline the key characteristics of the digital learning environment of the future, and opportunities for international collaborations, based on insights from the NGDLE, EDUCAUSE, Unizin, and IMS Global.